Modular Access to Boron Tripyrrolic Complexes from a Sequential Buchwald–Hartwig Amination/Boron Complexation Reaction
We report a modular synthesis of novel boron tripyrrolic analogs, BOTPY, via a sequential Buchwald-Hartwig amination/boron complexation reaction from readily accessible α,α-dibromodipyrromethenes. This approach provides facile access to structurally enriched B-, <i>meso</i>-, and α-positional functionalized fluorophores, possessing tunable absorption and fluorescence (Φ<sub>F</sub> up to 0.36) in the visible to NIR region as well as applicability for lipid droplet imaging.
Authors
- Qinghua Wu (ORCID: https://orcid.org/0000-0002-7252-7990)
- Yingjian Shang
- Erhong Hao
- Liang Zhang (ORCID: https://orcid.org/0000-0002-2694-1779)
- Guojun Li (ORCID: https://orcid.org/0000-0001-9505-1502)
- Wenlong Ma (ORCID: https://orcid.org/0000-0001-5102-9151)
- Wenxin Gu (ORCID: https://orcid.org/0009-0005-3578-4479)
- Lijuan Jiao
- Zhongxin Li (ORCID: https://orcid.org/0009-0000-7789-5234)
- Long Wang
Institutions
- Ministry of Education of the People's Republic of China (CN)
- Peking University (CN)
- Anhui University of Traditional Chinese Medicine (CN)
- Anhui Normal University (CN)
Publication Details
- Journal
- Organic Letters
- Published
- 2026-02-14
- DOI
- https://doi.org/10.1021/acs.orglett.6c00052
- Citations
- 1
- Primary Topic
- Organoboron and organosilicon chemistry
- Type
- article
- Field-Weighted Citation Impact
- 22.95