Efficacy of Microneedle Fractional Radiofrequency Combined With Platelet‐Rich Plasma for the Treatment of Melasma: A Split‐Face, Randomized Trial

MFR is an effective and safe option for melasma in patients with Fitzpatrick skin types III-IV. Adjunctive PRP did not further improve global clinical pigment scores or ultrasound-detected structural changes, but may offer added benefit for erythematous and pigmentary features detected by VISIA.

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Publication Details

Journal
Journal of Cosmetic Dermatology
Published
2026-02-01
DOI
https://doi.org/10.1111/jocd.70742
Primary Topic
Dermatologic Treatments and Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Efficacy of Microneedle Fractional Radiofrequency Combined With Platelet‐Rich Plasma for the Treatment of Melasma: A Split‐Face, Randomized Trial

Y. Chen, Yi Ou, Tingqiao Chen, Jin Chen et al.
Journal of Cosmetic Dermatology
Dermatologic Treatments and Research
article

Efficacy of Microneedle Fractional Radiofrequency Combined With Platelet‐Rich Plasma for the Treatment of Melasma: A Split‐Face, Randomized Trial

Y. Chen, Yi Ou, Tingqiao Chen, Jin Chen, Yuhao Li, Ziyan Chen
article en

Abstract

MFR is an effective and safe option for melasma in patients with Fitzpatrick skin types III-IV. Adjunctive PRP did not further improve global clinical pigment scores or ultrasound-detected structural changes, but may offer added benefit for erythematous and pigmentary features detected by VISIA.

Journal of Cosmetic DermatologyVol. 25(2)
The Affiliated Yongchuan Hospital of Chongqing Medical University (CN), Chongqing Medical University (CN)
Chongqing Science and Technology Commission, Chongqing Medical University
Openalex Percentile: Top 54%
Dermatologic Treatments and Research
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