Development of a dendritic cell-targeted vaccine strategy using proximity-induced conjugation
These findings underscore the potential of the PIC-based DC-targeted vaccine system to augment the immunogenicity, versatility, and therapeutic efficacy of cancer vaccines. This strategy offers a compelling solution to the challenges posed by antigenic drift and mutation, thereby improving clinical outcomes across a broad range of cancers.
Authors
- Xiaolin Yang (ORCID: https://orcid.org/0000-0002-4110-4805)
- Haodi Ma
- Yu J. Cao
- Guang Chen
- Zhidong Wang
- Jianjiang Li
- Zhengshuang Xu
Institutions
- Shenzhen University (CN)
- Shenzhen Bay Laboratory (CN)
Publication Details
- Journal
- Theranostics
- Published
- 2026-02-11
- DOI
- https://doi.org/10.7150/thno.122332
- Primary Topic
- Immunotherapy and Immune Responses
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Shenzhen Fundamental Research Program