Transbronchial photodynamic therapy for peripheral lung cancer – A pilot study

Lipiodol-assisted transbronchial PDT is technically feasible and demonstrated a favorable acute safety profile in this small pilot cohort. While the light dose (200 J/cm) resulted in modest tumor control, the technique successfully addressed the challenge of light delivery to peripheral lesions. Future Phase I trials with dose escalation are warranted.

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Publication Details

Journal
Photodiagnosis and Photodynamic Therapy
Published
2026-02-14
DOI
https://doi.org/10.1016/j.pdpdt.2026.105398
Primary Topic
Photodynamic Therapy Research Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Transbronchial photodynamic therapy for peripheral lung cancer – A pilot study

Yu-Chi Chiu, Yei-San Hsieh, Hwai-Luh Chang, S. W. Ricky Lee et al.
Photodiagnosis and Photodynamic Therapy
Photodynamic Therapy Research Studies
article

Transbronchial photodynamic therapy for peripheral lung cancer – A pilot study

Yu-Chi Chiu, Yei-San Hsieh, Hwai-Luh Chang, S. W. Ricky Lee, H Chao, Cho-yin Lee, Chi Ming Lee, Yen-Lin Wu, Jih-Tung Pai
article en

Abstract

Lipiodol-assisted transbronchial PDT is technically feasible and demonstrated a favorable acute safety profile in this small pilot cohort. While the light dose (200 J/cm) resulted in modest tumor control, the technique successfully addressed the challenge of light delivery to peripheral lesions. Future Phase I trials with dose escalation are warranted.

Photodiagnosis and Photodynamic TherapyVol. 58
China Medical University (TW), Taipei Veterans General Hospital (TW), Tao Yuan General Hospital (TW)
Good health and well-being
Openalex Percentile: Top 56%
Photodynamic Therapy Research Studies
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