Comparative efficacy of digital health interventions for depression and anxiety symptoms in adolescents and young adults: a systematic review and bayesian network meta-analysis

Digital health interventions, particularly CBT-based interventions (CBT-DI), were associated with statistically significant improvements in anxiety symptoms. For depression, while CBT-DI ranked highest in probability, it did not demonstrate statistical superiority over controls. Given the imprecision in effect estimates, CBT-DI may be considered a potential complementary measure within a stepped-care mental health system. Results should be interpreted with caution due to wide credible intervals, and further high-quality studies are required to confirm these findings.