Identifying Chronic Lymphocytic Leukaemia and Small Lymphocytic Lymphoma: An Uncommon Case of Ocular Adnexal Lymphoma
Chronic lymphocytic leukaemia (CLL) and small lymphocytic lymphoma (SLL) are typically classified and treated as different manifestations of the same disease. Compared to the Western hemisphere, this type of lymphoma is rare in Asian countries. They usually manifest as anaemia, organomegaly, or lymphadenopathy. Ocular adnexal lymphoma (OAL) is a rare presentation of lymphoma that can affect any part of the orbital region. We present a gentleman who sought treatment at our centre for this rare malignancy, with an atypical presentation of painless swelling over the upper eyelid. The initial diagnosis of hematoma secondary to trauma was swiftly discarded following surgery, revealing a lobulated mass. Subsequently, histopathological examination points towards a diagnosis of CLL/SLL. We illustrate the importance of multidisciplinary management with several departments, striving to achieve the best possible outcome.
Authors
- Xiong Khee Cheong (ORCID: https://orcid.org/0000-0002-2859-1055)
- Nordashima Abd Shukor (ORCID: https://orcid.org/0000-0003-2493-4724)
- Sivakumar Palaniappan (ORCID: https://orcid.org/0000-0001-9535-3623)
- Nor Rafeah Tumian (ORCID: https://orcid.org/0000-0001-6124-8120)
- Subo Chang
- Alia Suzana Asri (ORCID: https://orcid.org/0000-0002-2477-8613)
- Juen Kiem Tan (ORCID: https://orcid.org/0000-0001-8904-9799)
- Chia Yin Chong (ORCID: https://orcid.org/0000-0002-0346-2388)
- S Fadilah Abdul Wahid
- Othmaliza O
Institutions
- Hospital Kuala Lumpur (MY)
- University Kebangsaan Malaysia Medical Centre (MY)
- National University of Malaysia (MY)
Publication Details
- Journal
- Cureus
- Published
- 2026-02-14
- DOI
- https://doi.org/10.7759/cureus.103586
- Primary Topic
- Chronic Lymphocytic Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00