Independent risk of death from hemorrhage and traumatic brain injury in polytrauma: findings from a prospective, multi-center study in the Western Cape of South Africa
Increasing severity of hemorrhage and TBI are both independently associated with a three to five times higher rate of 7-day mortality. These findings highlight the importance of timely hemorrhage control and resuscitation to reduce mortality and the risk of progression to severe disease.
Authors
- Jessica Wild (ORCID: https://orcid.org/0000-0002-2927-8239)
- Hendrick J. Lategan
- Elmin Steyn (ORCID: https://orcid.org/0000-0002-8090-1559)
- Denise Lourens
- Lesley Hodsdon
- Adriaan Vlok (ORCID: https://orcid.org/0000-0002-3202-2867)
- Janette Verster (ORCID: https://orcid.org/0000-0002-1273-5456)
- J.A. Dixon
- Karlien Doubell
- Craig Wylie (ORCID: https://orcid.org/0000-0003-2168-4838)
- Nee‐Kofi Mould‐Millman (ORCID: https://orcid.org/0000-0003-4303-6903)
- Shaheem de Vries (ORCID: https://orcid.org/0000-0003-3986-1652)
- Maria Kohlbrenner
- Leigh Wagner
- Mengli Xiao (ORCID: https://orcid.org/0000-0003-4974-3588)
- George Oosthuizen
- EpiC Study Site Collaborators
- L’Oreal Snyders
- Mohammed Mayet
- Steven G. Schauer
- Willem Stassen
Institutions
- Western Cape Department of Health (ZA)
- Colorado School of Public Health (US)
- University of Cape Town (ZA)
- Stellenbosch University (ZA)
- Government of South Africa (ZA)
- United States Army Institute of Surgical Research (US)
- Right to Care (ZA)
- Centre for Environmental Rights (ZA)
- University of Colorado Anschutz Medical Campus (US)
- University of Colorado Denver (US)
Publication Details
- Journal
- World Journal of Emergency Surgery
- Published
- 2026-02-14
- DOI
- https://doi.org/10.1186/s13017-026-00677-z
- Primary Topic
- Trauma and Emergency Care Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00