Clinical Performance of a Mp1p Antibody Detection Immunoassay For Talaromycosis
The anti-Mp1p IgM and IgG EIAs show low utility for the diagnosis of acute talaromycosis. However, at the high specificity cut-off of 95%, the assays have utility in the detection of <i>T. marneffei</i> exposure at both individual and population levels, and. provides a foundation for future sero-epidemiological studies.
Authors
- Lottie Brown (ORCID: https://orcid.org/0000-0001-9896-8682)
- Helen Xu (ORCID: https://orcid.org/0009-0001-5766-9130)
- Nguyễn Thị Mai Thu
- Shanti Narayanasamy (ORCID: https://orcid.org/0000-0002-6667-2868)
- Ngô Thị Hoa (ORCID: https://orcid.org/0000-0001-9320-4050)
- Sruthi Venugopalan (ORCID: https://orcid.org/0009-0005-5577-4120)
- Joseph Egger (ORCID: https://orcid.org/0000-0002-6885-5318)
- V C Ly
- Thuy Le
- Matthew T Burke
Institutions
- University of Nevada, Reno (US)
- St George's, University of London (GB)
- Duke University (US)
- Pham Ngoc Thach University of Medicine (VN)
- St George’s University Hospitals NHS Foundation Trust (GB)
- University of Medicine and Pharmacy at Ho Chi Minh City (VN)
- University of Oxford (GB)
- St George's Hospital (GB)
- Duke Institute for Health Innovation (US)
- Oxford University Clinical Research Unit (VN)
- Hospital for Tropical Diseases (VN)
- Austin Health (AU)
- Institute of Infection and Immunity (CA)
Publication Details
- Journal
- medRxiv
- Published
- 2026-02-14
- DOI
- https://doi.org/10.64898/2026.02.08.26344333
- Primary Topic
- Fungal Infections and Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- Center for AIDS Research, University of Washington
- National Institute of Allergy and Infectious Diseases