Evaluation of Efficacy of Bupivacaine vs Articaine for Postoperative Pain Management in Open Reduction of Fracture of Mandible- an in vivo study
Aim: To evaluate the efficacy of 0.5% Bupivacaine and 4% Articaine when administered via inferior alveolar nerve block (IANB) in patients undergoing surgical management of mandibular fractures. Material and Method: The sample consisted of 40 participants, who required management of mandibular fractures. Results: Patients receiving Bupivacaine required rescue analgesia significantly later (10.40 h) compared to those receiving Articaine (7.30 h), with a mean difference of 3.10 h ( P < 0.001). This 42% delay in rescue analgesic requirement represents a clinically meaningful improvement in postoperative pain management, potentially reducing overall analgesic consumption and associated side effects while improving patient satisfaction scores.
Authors
- Saksham Nahar
- Neha Jain (ORCID: https://orcid.org/0000-0003-2663-6034)
- Annant Choubey
- Pushpraj Singh
- Dheeraj Sharma
- Ajay K. Pillai
Institutions
- People’s University (IN)
Publication Details
- Journal
- Journal of Pharmacy And Bioallied Sciences
- Published
- 2026-02-14
- DOI
- https://doi.org/10.4103/jpbs.jpbs_1268_25
- Primary Topic
- Dental Anxiety and Anesthesia Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00