Evaluation of Efficacy of Bupivacaine vs Articaine for Postoperative Pain Management in Open Reduction of Fracture of Mandible- an in vivo study

Aim: To evaluate the efficacy of 0.5% Bupivacaine and 4% Articaine when administered via inferior alveolar nerve block (IANB) in patients undergoing surgical management of mandibular fractures. Material and Method: The sample consisted of 40 participants, who required management of mandibular fractures. Results: Patients receiving Bupivacaine required rescue analgesia significantly later (10.40 h) compared to those receiving Articaine (7.30 h), with a mean difference of 3.10 h ( P < 0.001). This 42% delay in rescue analgesic requirement represents a clinically meaningful improvement in postoperative pain management, potentially reducing overall analgesic consumption and associated side effects while improving patient satisfaction scores.

Authors

Institutions

Publication Details

Journal
Journal of Pharmacy And Bioallied Sciences
Published
2026-02-14
DOI
https://doi.org/10.4103/jpbs.jpbs_1268_25
Primary Topic
Dental Anxiety and Anesthesia Techniques
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Evaluation of Efficacy of Bupivacaine vs Articaine for Postoperative Pain Management in Open Reduction of Fracture of Mandible- an in vivo study

Saksham Nahar, Neha Jain, Annant Choubey, Pushpraj Singh et al.
Journal of Pharmacy And Bioallied Sciences
Dental Anxiety and Anesthesia Techniques
article

Evaluation of Efficacy of Bupivacaine vs Articaine for Postoperative Pain Management in Open Reduction of Fracture of Mandible- an in vivo study

Saksham Nahar, Neha Jain, Annant Choubey, Pushpraj Singh, Dheeraj Sharma, Ajay K. Pillai
article en

Abstract

Aim: To evaluate the efficacy of 0.5% Bupivacaine and 4% Articaine when administered via inferior alveolar nerve block (IANB) in patients undergoing surgical management of mandibular fractures. Material and Method: The sample consisted of 40 participants, who required management of mandibular fractures. Results: Patients receiving Bupivacaine required rescue analgesia significantly later (10.40 h) compared to those receiving Articaine (7.30 h), with a mean difference of 3.10 h ( P < 0.001). This 42% delay in rescue analgesic requirement represents a clinically meaningful improvement in postoperative pain management, potentially reducing overall analgesic consumption and associated side effects while improving patient satisfaction scores.

Journal of Pharmacy And Bioallied SciencesVol. 18(2)
People’s University (IN)
Openalex Percentile: Top 56%
Dental Anxiety and Anesthesia Techniques
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.