Pharmacotherapy for Alcohol Craving Reduction: Efficacy of Short-Term Treatments in Alcohol Use Disorder
This review suggests that naltrexone and varenicline appear to be the most consistently supported short-term pharmacotherapies for alcohol craving within the available evidence, with promising but less consistent findings for memantine, acamprosate, and topiramate. These results highlight potential candidates for immediate craving management in AUD, while underscoring the need for larger and longer-term trials to confirm their efficacy and safety.
Authors
- Matheus Cheibub David Marin
- Giuliana Perrotte (ORCID: https://orcid.org/0000-0003-3893-1743)
- Maria Olívia Pozzolo Pedro (ORCID: https://orcid.org/0000-0003-1336-093X)
- João Mauricio Castaldelli-Maia
Institutions
- Universidade de São Paulo (BR)
Publication Details
- Journal
- Medicines
- Published
- 2026-02-14
- DOI
- https://doi.org/10.3390/medicines13010007
- Primary Topic
- Substance Abuse Treatment and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00