A Rare Cause of Life-Threatening Chest Pain: Kounis Syndrome

Kounis syndrome, defined as an acute coronary syndrome triggered by allergic or hypersensitivity reactions, is a rare yet potentially life-threatening condition. This report details the case of a 50-year-old female patient presenting with recurrent chest pain, hypereosinophilia, and allergic comorbidities, who was ultimately diagnosed with type I Kounis syndrome. Modifications to her treatment regimen, including the administration of diltiazem and prednisolone, led to a complete resolution of her symptoms. This case highlights the critical importance of early diagnosis and timely intervention in managing Kounis syndrome. Early recognition is essential to prevent potentially fatal outcomes, thereby emphasizing the need for increased awareness among healthcare professionals.

Authors

Institutions

Publication Details

Journal
Journal of Cardiovascular Development and Disease
Published
2026-02-14
DOI
https://doi.org/10.3390/jcdd13020094
Primary Topic
Food Allergy and Anaphylaxis Research
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

A Rare Cause of Life-Threatening Chest Pain: Kounis Syndrome

Yabin Liu, Xi Chen, Liangliang Jia, Yufei Wang
Journal of Cardiovascular Development and Disease
Food Allergy and Anaphylaxis Research
article

A Rare Cause of Life-Threatening Chest Pain: Kounis Syndrome

Yabin Liu, Xi Chen, Liangliang Jia, Yufei Wang
article en

Abstract

Kounis syndrome, defined as an acute coronary syndrome triggered by allergic or hypersensitivity reactions, is a rare yet potentially life-threatening condition. This report details the case of a 50-year-old female patient presenting with recurrent chest pain, hypereosinophilia, and allergic comorbidities, who was ultimately diagnosed with type I Kounis syndrome. Modifications to her treatment regimen, including the administration of diltiazem and prednisolone, led to a complete resolution of her symptoms. This case highlights the critical importance of early diagnosis and timely intervention in managing Kounis syndrome. Early recognition is essential to prevent potentially fatal outcomes, thereby emphasizing the need for increased awareness among healthcare professionals.

Journal of Cardiovascular Development and DiseaseVol. 13(2)
Implant Sciences (United States) (US), Blood Center of Zhejiang Province (CN), Second Affiliated Hospital of Zhejiang University (CN)
Good health and well-being, Gender equality
Openalex Percentile: Top 48%
Food Allergy and Anaphylaxis Research
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.