Peptide amphiphile nanofibers: advanced drug delivery platforms for cardiovascular therapeutics
Despite their complexity, peptide amphiphile nanofibers offer a promising platform through which to deliver nanotherapeutics to treat cardiovascular disease. The future involves further development and evaluation of this technology in large animal models to strengthen translational data, discovery of additional physiologic targets, large scale standardized production, and incorporation of novel therapeutics. Importantly, we look forward to incorporating antioxidants into our existing peptide amphiphile nanofiber delivery vehicles to hopefully produce a synergistic effect of our targeted therapeutics.
Authors
- Nick D. Tsihlis (ORCID: https://orcid.org/0000-0002-0410-0143)
- Behzad S. Farivar (ORCID: https://orcid.org/0000-0002-7983-9647)
- Adelso Tejada Jackson (ORCID: https://orcid.org/0000-0003-3280-9843)
- Katherine I. Foley
Institutions
- University of Virginia (US)
- The University of Texas Health Science Center at Houston (US)
Publication Details
- Journal
- Expert Opinion on Drug Delivery
- Published
- 2026-02-14
- DOI
- https://doi.org/10.1080/17425247.2026.2631770
- Primary Topic
- Supramolecular Self-Assembly in Materials
- Type
- article
- Field-Weighted Citation Impact
- 0.00