Ashy dermatosis-like hyperpigmentation limited to the arms associated with osimertinib therapy
A 66-year-old man receiving osimertinib for lung adenocarcinoma developed multiple asymptomatic slate-grey macules on photo-exposed forearms. Histopathology showed basal vacuolar change with pigment incontinence. Recognizing this drug-related pattern allows continuation of effective anticancer therapy.
Authors
- Takahiro Kobayashi
- Yasuyuki Fujita (ORCID: https://orcid.org/0000-0001-7934-9261)
- Shin Iinuma
- Akemi Ishida-Yamamoto
Institutions
- Asahikawa Medical University (JP)
- Japanese Red Cross Hokkaido College of Nursing (JP)
Publication Details
- Journal
- Clinical and Experimental Dermatology
- Published
- 2026-02-13
- DOI
- https://doi.org/10.1093/ced/llag085
- Citations
- 1
- Primary Topic
- Colorectal Cancer Treatments and Studies
- Type
- article
- Field-Weighted Citation Impact
- 24.20