Blocking AREG-EGFR signaling attenuates pan-arterial fibrosis in chronic cardiac allograft rejection
Pan-arterial fibrosis represents a unifying pathological process across major vascular territories in CAV. Targeting fibrotic remodeling may offer a promising adjunctive strategy to improve long-term graft outcomes.
Authors
- Yixuan Sheng (ORCID: https://orcid.org/0000-0003-1022-7690)
- Yuqi An
- Xingchao Du
- Kai Xing (ORCID: https://orcid.org/0000-0001-7087-0157)
- Mengda Xu
- Jiangping Song
- Jian Huang
- Yuan Chang
- Hao Liu
- Xiaofei Zhu
- Peiyuan Li
- Xiao Chen
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking University (CN)
- Kunming Medical University (CN)
- Beijing Jishuitan Hospital (CN)
- First Teaching Hospital of Tianjin University of Traditional Chinese Medicine (CN)
- Sanya University (CN)
- Fu Wai Hospital (CN)
- China Agricultural University (CN)
Publication Details
- Journal
- Theranostics
- Published
- 2026-02-11
- DOI
- https://doi.org/10.7150/thno.125318
- Primary Topic
- Transplantation: Methods and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00