An update on the developments and challenges with the diagnosis and classification of autoimmune optic neuritis

Real-world improvements will depend on standardized diagnostic pathways integrating orbital magnetic resonance imaging (MRI), high-quality antibody assays, OCT, and visual evoked potentials (VEP). Fluid biomarkers such as serum neurofilament light chain (sNfL) and serum glial fibrillary acidic protein (sGFAP), together with AI-supported analytics, may refine risk estimates, especially in seronegative cases.

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Publication Details

Journal
Expert Review of Neurotherapeutics
Published
2026-02-14
DOI
https://doi.org/10.1080/14737175.2026.2632795
Primary Topic
Multiple Sclerosis Research Studies
Type
article
Field-Weighted Citation Impact
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article

An update on the developments and challenges with the diagnosis and classification of autoimmune optic neuritis

Charlotte Bereuter, Jan Schroeter, Frederike Cosima Oertel, Murat Delikaya et al.
Expert Review of Neurotherapeutics
Multiple Sclerosis Research Studies
article

An update on the developments and challenges with the diagnosis and classification of autoimmune optic neuritis

Charlotte Bereuter, Jan Schroeter, Frederike Cosima Oertel, Murat Delikaya, Roua Hamdi
article en

Abstract

Real-world improvements will depend on standardized diagnostic pathways integrating orbital magnetic resonance imaging (MRI), high-quality antibody assays, OCT, and visual evoked potentials (VEP). Fluid biomarkers such as serum neurofilament light chain (sNfL) and serum glial fibrillary acidic protein (sGFAP), together with AI-supported analytics, may refine risk estimates, especially in seronegative cases.

Expert Review of Neurotherapeutics
Humboldt-Universität zu Berlin (DE), Einstein Center Digital Future (DE), Freie Universität Berlin (DE), Charité - Universitätsmedizin Berlin (DE)
Good health and well-being
Openalex Percentile: Top 57%
Multiple Sclerosis Research Studies
DOISourceOpenAlex
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An update on the developments and challenges with the diagnosis and classification of autoimmune optic neuritis — Charlotte Bereuter, Jan Schroeter, et al. · Expert Review of Neurotherapeutics (2026) | TGRS Research Map | TGRS