Recent Advances in AI and GenAI for Health Informatics

The emergence of large language models (LLMs) and generative artificial intelligence (GenAI) has marked a turning point in health informatics. AI has become a very helpful tool for health informatics applications, with numerous AI applications in health informatics being reported in the last years. The objective of this paper is to synthesize the common concerns and opportunities raised by recent popular reviews on AI and health informatics. The main methodological topics covered in this up-to-date review include traditional AI, GenAI, and LLMs. The literature search was conducted through the popular academic database Scopus, which covers over one hundred million records, including both computer science and healthcare. Among these popular reviews (measured by the number of citations that each one received), clinical decision support, patient care, electronic health records, hospital management, and remote patient monitoring are the most mentioned healthcare topics. Different from the majority of the existing reviews that narrowly cover on one to a few topics in healthcare, our review is designed with the objective to provide a broad coverage, such that practitioners may benefit from comprehensive insights covering the above mentioned five popular topics in AI health informatics applications. Based on an in-depth analysis of these reviews by human experts, the main AI tools used, their main challenges, and some future directions have been identified in our investigation. Patient privacy, cybersecurity, ethics, clinical accountability, engaging health professionals, benchmarks and standardization, as well as lack of explainability are the common concerns identified from the literature covered in this review.

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Publication Details

Journal
Healthcare
Published
2026-02-14
DOI
https://doi.org/10.3390/healthcare14040495
Primary Topic
Artificial Intelligence in Healthcare and Education
Type
article
Field-Weighted Citation Impact
0.00
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article

Recent Advances in AI and GenAI for Health Informatics

Vasile Palade, Danina Kapetanovic, Mike Gourlay, Suzy Araujo et al.
Healthcare
Artificial Intelligence in Healthcare and Education
article

Recent Advances in AI and GenAI for Health Informatics

Vasile Palade, Danina Kapetanovic, Mike Gourlay, Suzy Araujo, Sio Iong Ao, Chris Holt
article en

Abstract

The emergence of large language models (LLMs) and generative artificial intelligence (GenAI) has marked a turning point in health informatics. AI has become a very helpful tool for health informatics applications, with numerous AI applications in health informatics being reported in the last years. The objective of this paper is to synthesize the common concerns and opportunities raised by recent popular reviews on AI and health informatics. The main methodological topics covered in this up-to-date review include traditional AI, GenAI, and LLMs. The literature search was conducted through the popular academic database Scopus, which covers over one hundred million records, including both computer science and healthcare. Among these popular reviews (measured by the number of citations that each one received), clinical decision support, patient care, electronic health records, hospital management, and remote patient monitoring are the most mentioned healthcare topics. Different from the majority of the existing reviews that narrowly cover on one to a few topics in healthcare, our review is designed with the objective to provide a broad coverage, such that practitioners may benefit from comprehensive insights covering the above mentioned five popular topics in AI health informatics applications. Based on an in-depth analysis of these reviews by human experts, the main AI tools used, their main challenges, and some future directions have been identified in our investigation. Patient privacy, cybersecurity, ethics, clinical accountability, engaging health professionals, benchmarks and standardization, as well as lack of explainability are the common concerns identified from the literature covered in this review.

HealthcareVol. 14(4)
University of Waterloo (CA), Regional Municipality of Waterloo (CA), Coventry University (GB)
Peace, Justice and strong institutions
Openalex Percentile: Top 56%
Artificial Intelligence in Healthcare and Education
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