Glucagon-like peptide-1 receptor agonist use and clinical outcomes after lung transplantation: A single-center cohort study

In this small, retrospective cohort with limited GLP-1 RA exposure, GLP-1 RA use before and early after transplantation was not associated with worse early or late outcomes, including CLAD and mortality, and was generally well tolerated. These results are reassuring but should be interpreted cautiously; prospective studies in larger cohorts are needed to confirm safety and to define optimal patient selection and timing.

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Publication Details

Journal
JHLT Open
Published
2026-02-14
DOI
https://doi.org/10.1016/j.jhlto.2026.100513
Primary Topic
Transplantation: Methods and Outcomes
Type
article
Field-Weighted Citation Impact
0.00
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article

Glucagon-like peptide-1 receptor agonist use and clinical outcomes after lung transplantation: A single-center cohort study

Yuriko Yagi, Yudai Miyashita, Taisuke Kaiho, Chitaru Kurihara et al.
JHLT Open
Transplantation: Methods and Outcomes
article

Glucagon-like peptide-1 receptor agonist use and clinical outcomes after lung transplantation: A single-center cohort study

Yuriko Yagi, Yudai Miyashita, Taisuke Kaiho, Chitaru Kurihara, Rachel Reinchenbach, Ambalavan Arunachalam
article en

Abstract

In this small, retrospective cohort with limited GLP-1 RA exposure, GLP-1 RA use before and early after transplantation was not associated with worse early or late outcomes, including CLAD and mortality, and was generally well tolerated. These results are reassuring but should be interpreted cautiously; prospective studies in larger cohorts are needed to confirm safety and to define optimal patient selection and timing.

JHLT OpenVol. 12
Northwestern University (US)
Good health and well-being
Openalex Percentile: Top 55%
Transplantation: Methods and Outcomes
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