Citraconic acid mitigates radiation-induced intestinal injury by modulating IL-17 signaling to enhance epithelial regeneration
CA exerts protective effects against radiation-induced intestinal injury by modulating the IL-17-related signaling network, thereby promoting intestinal epithelial regeneration and barrier repair. These findings suggest that CA may represent a potential metabolic intervention strategy for the prevention and treatment of radiation-induced gastrointestinal damage.
Authors
- Xiaojie Liu (ORCID: https://orcid.org/0000-0002-0006-9468)
- Maoxian Yang
- Jiangchen Liu
- Liu Feng
Institutions
- King's College London (GB)
- First Hospital of Jiaxing (CN)
Publication Details
- Journal
- BMC Gastroenterology
- Published
- 2026-02-14
- DOI
- https://doi.org/10.1186/s12876-026-04689-6
- Primary Topic
- Effects of Radiation Exposure
- Type
- article
- Field-Weighted Citation Impact
- 0.00