Neuropsychological Profile of Normal Pressure Hydrocephalus: A Systematic Review of Cognitive Trajectories and Evidence-Based Assessment Tools for Surgical Management
Cognitive recovery after shunt in NPH follows a predominantly fronto-subcortical pattern, with the greatest improvements occurring within the first postoperative year. MMSE, TMT-A, TMT-B, and Digit Span represent the most reliable and informative neuropsychological tools for preoperative and postoperative evaluation and should constitute the core of a standardized NPH-specific cognitive battery. Establishing uniform testing protocols and improving methodological consistency across studies will enhance diagnostic accuracy, surgical decision-making, and long-term monitoring of this treatable condition.
Authors
- Gianluca Scalia (ORCID: https://orcid.org/0000-0002-9465-2506)
- Grazia Razza (ORCID: https://orcid.org/0000-0001-9896-143X)
- Rosalba Pitoia
- Francesca Graziano
- Giovanni Nicoletti
- Roberta Finocchiaro
- Lisa Passarello
Institutions
- University of Catania (IT)
- Ospedale Garibaldi (IT)
Publication Details
- Journal
- World Neurosurgery
- Published
- 2026-02-14
- DOI
- https://doi.org/10.1016/j.wneu.2026.124868
- Primary Topic
- Cerebrospinal fluid and hydrocephalus
- Type
- article
- Field-Weighted Citation Impact
- 0.00