CD20 molecule deficiency and carrier frequency: a village-based screening study

CD20 MFI, rather than CD20 percentage, appears to be a more informative indicator for identifying individuals with flow-cytometric patterns suggestive of putative carrier status. Flow cytometry may serve as a rapid and practical preliminary screening tool in community-based settings; however, confirmation of carrier status requires molecular genetic testing, and genetic counseling should be based on verified genotypic results.

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Publication Details

Journal
TURKISH JOURNAL OF MEDICAL SCIENCES
Published
2026-02-12
DOI
https://doi.org/10.55730/1300-0144.6157
Primary Topic
Immunodeficiency and Autoimmune Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

CD20 molecule deficiency and carrier frequency: a village-based screening study

Mehmet Ali Karaselek, Mustafa Gençeli, Sevgi Keleş, Ayşe Sümeyra Engin et al.
TURKISH JOURNAL OF MEDICAL SCIENCES
Immunodeficiency and Autoimmune Disorders
article

CD20 molecule deficiency and carrier frequency: a village-based screening study

Mehmet Ali Karaselek, Mustafa Gençeli, Sevgi Keleş, Ayşe Sümeyra Engin, Serkan Küççüktürk, Tuğçe Duran, TUĞBA ESRA PEKCANDANOĞLU, NAZİRE NUR ONAT, MUHAMMED FURKAN ERDEN, ŞÜKRÜ NAİL GÜNER, BİLAL BOSTAN, BÜŞRA YÜKSEL, MAHMUT ESAD YURTSEVEN, İSMAİL REİSLİ, EBRU SÜMEN
article en

Abstract

CD20 MFI, rather than CD20 percentage, appears to be a more informative indicator for identifying individuals with flow-cytometric patterns suggestive of putative carrier status. Flow cytometry may serve as a rapid and practical preliminary screening tool in community-based settings; however, confirmation of carrier status requires molecular genetic testing, and genetic counseling should be based on verified genotypic results.

TURKISH JOURNAL OF MEDICAL SCIENCESVol. 56(1)
Necmettin Erbakan University (TR), KTO Karatay University (TR), Karamanoğlu Mehmetbey University (TR)
Openalex Percentile: Top 54%
Immunodeficiency and Autoimmune Disorders
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