CYTOTOXIC EFFICIENCY AND ANTIPROLIFERATIVE ACTIVITY OF THE ISOLATED COMPOUND AND ATROPINE FROM DATURA STRAMONIUM SEEDS AGAINST HIGHLY METASTATIC CERVICAL CANCER HELA CELL

The main aim of the present research study was to evaluate the antiproliferative activity against the highly metastatic cervical cancer of the compound isolated from the acetone extract of the seeds and atropine of Datura stramonium. Using MTT assay the cytotoxic assay was calculated. Significant morphological changes were observed in a dose dependent manner when treated with acetone extracts of D. stramonium. For further investigation of the active principles this recent work gives a push for the much needed treatment against the metastatic cervical cancer.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-02-14
DOI
https://doi.org/10.5281/zenodo.18638612
Primary Topic
Phytochemicals and Medicinal Plants
Type
article
Field-Weighted Citation Impact
0.00
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article

CYTOTOXIC EFFICIENCY AND ANTIPROLIFERATIVE ACTIVITY OF THE ISOLATED COMPOUND AND ATROPINE FROM DATURA STRAMONIUM SEEDS AGAINST HIGHLY METASTATIC CERVICAL CANCER HELA CELL

Monisha Banerjee, Shama Parveen, Meenakshi Singh, Ana Ahtsham et al.
Zenodo (CERN European Organization for Nuclear Research)
Phytochemicals and Medicinal Plants
article

CYTOTOXIC EFFICIENCY AND ANTIPROLIFERATIVE ACTIVITY OF THE ISOLATED COMPOUND AND ATROPINE FROM DATURA STRAMONIUM SEEDS AGAINST HIGHLY METASTATIC CERVICAL CANCER HELA CELL

Monisha Banerjee, Shama Parveen, Meenakshi Singh, Ana Ahtsham, Zoya Amreen, Shriyansha
article en

Abstract

The main aim of the present research study was to evaluate the antiproliferative activity against the highly metastatic cervical cancer of the compound isolated from the acetone extract of the seeds and atropine of Datura stramonium. Using MTT assay the cytotoxic assay was calculated. Significant morphological changes were observed in a dose dependent manner when treated with acetone extracts of D. stramonium. For further investigation of the active principles this recent work gives a push for the much needed treatment against the metastatic cervical cancer.

Zenodo (CERN European Organization for Nuclear Research)
University of Lucknow (IN)
Good health and well-being
Openalex Percentile: Top 55%
Phytochemicals and Medicinal Plants
DOIOpen Access PDFOpenAlex
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CYTOTOXIC EFFICIENCY AND ANTIPROLIFERATIVE ACTIVITY OF THE ISOLATED COMPOUND AND ATROPINE FROM DATURA STRAMONIUM SEEDS AGAINST HIGHLY METASTATIC CERVICAL CANCER HELA CELL — Monisha Banerjee, Shama Parveen, et al. · Zenodo (CERN European Organization for Nuclear Research) (2026) | TGRS Research Map | TGRS