Minor trauma-induced eccrine porocarcinoma of the toe in a patient on long-term carbamazepine: a case report and literature review
This case highlights the importance of considering rare malignancies like Eccrine Porocarcinoma in the differential diagnosis of non-healing acral ulcers. An early biopsy is crucial. The long-term use of carbamazepine in this context is noted, and its potential role as a co-factor in tumor development, possibly interacting with local chronic inflammation, is discussed. Further investigation into the influence of systemic medications on the pathogenesis of such rare tumors is warranted.
Authors
- Jiabin Lin (ORCID: https://orcid.org/0009-0005-4332-3154)
- Yifan Wang (ORCID: https://orcid.org/0000-0001-7056-6251)
- Xinyu Zhao (ORCID: https://orcid.org/0000-0002-5128-4424)
- Jinghang Lv
- Haidong Liang
- Lianbo Yang
- Xinyao Cui
- Ziang Zheng
Institutions
- Dalian Medical University (CN)
- Second Affiliated Hospital of Dalian Medical University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2026-02-13
- DOI
- https://doi.org/10.3389/fonc.2026.1727762
- Primary Topic
- Cancer and Skin Lesions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Dalian Medical University