Comparable survival outcome with anti-EGFR therapy in any treatment line in left-sided metastatic colorectal cancer

While earlier line use confers longer PFS, OS remains similar regardless of the timing of anti-EGFR therapy. These findings support the introduction of anti-EGFR agents at any line when feasible, highlighting that ensuring access may be more important than timing in treatment sequencing.

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Publication Details

Journal
Journal of Gastrointestinal Oncology
Published
2026-02-01
DOI
https://doi.org/10.21037/jgo-2025-811
Primary Topic
Colorectal Cancer Treatments and Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Comparable survival outcome with anti-EGFR therapy in any treatment line in left-sided metastatic colorectal cancer

Krittiya Korphaisarn, Anita Archwamety, Charuwan Akewanlop
Journal of Gastrointestinal Oncology
Colorectal Cancer Treatments and Studies
article

Comparable survival outcome with anti-EGFR therapy in any treatment line in left-sided metastatic colorectal cancer

Krittiya Korphaisarn, Anita Archwamety, Charuwan Akewanlop
article en

Abstract

While earlier line use confers longer PFS, OS remains similar regardless of the timing of anti-EGFR therapy. These findings support the introduction of anti-EGFR agents at any line when feasible, highlighting that ensuring access may be more important than timing in treatment sequencing.

Journal of Gastrointestinal OncologyVol. 17(1)
Siriraj Hospital (TH), Mahidol University (TH)
Good health and well-being
Openalex Percentile: Top 56%
Colorectal Cancer Treatments and Studies
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