Evaluation of bi-atrial dynamic electrophysiological properties in atrial septal defect patients
Right atrial remodelling, characterised by atrial dilatation and increased low voltage, is present in ASD patients. During fixed rate pacing, conduction and repolarisation properties are similar between ASD and AF patients. However, the restitution properties of both conduction and repolarisation are more pronounced in ASD than AF patients.
Authors
- Vivienne Ezzat
- S. Niederer
- Mark O’Neill (ORCID: https://orcid.org/0000-0002-6070-7177)
- Keeran Vickneson (ORCID: https://orcid.org/0000-0002-2413-4770)
- Alessandra Frigiola (ORCID: https://orcid.org/0000-0001-5932-4200)
- Steven E. Williams (ORCID: https://orcid.org/0000-0002-7266-2084)
- Una Buckley (ORCID: https://orcid.org/0000-0002-4107-1054)
- Matthew Jones (ORCID: https://orcid.org/0000-0002-2006-3426)
- Iain Sim
- Louisa O’Neill
- John Whitaker
- Ali Gharaviri
- Daniel O’Hare
- Matthew Wright
- Rahul Mukherjee
Institutions
- King's College London (GB)
- Guy's and St Thomas' NHS Foundation Trust (GB)
- Art Research Centre of the Slovak Academy of Sciences (SK)
- Thomas Foundation (AU)
- University of Edinburgh (GB)
Publication Details
- Journal
- Frontiers in Physiology
- Published
- 2026-02-13
- DOI
- https://doi.org/10.3389/fphys.2025.1705582
- Primary Topic
- Atrial Fibrillation Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- NIHR Biomedical Research Centre, Royal Marsden NHS Foundation Trust/Institute of Cancer Research
- National Institute for Health and Care Research
- British Heart Foundation
- King's College London
- Engineering and Physical Sciences Research Council
- Centre For Medical Engineering, King’s College London
- Biosense Webster