Association of geriatric nutritional risk index with metabolic dysfunction-associated steatotic liver disease and subtypes in Chinese elderly: identification of an overnutrition risk threshold and implications for extended risk stratification
Elevated GNRI significantly increases MASLD and subtype risks in Chinese elderly, with GNRI ≥107.59 identified as a critical threshold for escalating the risk of MASLD. These findings support extending GNRI's risk stratification to overnutrition monitoring, enabling prioritized screening for metabolic hazards. Future research should validate this threshold's clinical utility, establish evidence-based upper limits for overnutrition risk, and explore GNRI's role in MASLD pathogenesis.
Authors
- Qiuyun Kang
- Mingxin Guo (ORCID: https://orcid.org/0000-0001-8401-5952)
- Tianran Shen (ORCID: https://orcid.org/0009-0002-7466-3379)
- Haiyan Chen
- Haixin Lyu
- Zegeng Zhan
- Yangyang Qin
- Lifang Mao
Institutions
- Guangdong Pharmaceutical University (CN)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2026-02-13
- DOI
- https://doi.org/10.3389/fnut.2026.1743679
- Primary Topic
- Nutrition and Health in Aging
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China