Accuracy and Reproducibility of Different Artificial Intelligence Chatbots’ Responses to Patient-Based Vitreoretinal Questions: A Comparative Study

ChatGPT-5.o and DeepSeek R1 approached high accuracy and reproducibility comparable to clinical standards, indicating potential as patient-education tools in vitreoretinal care. However, variability across models and disease categories highlights the need for cautious clinical adoption and continued optimization to ensure safe, reliable information delivery.

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Publication Details

Journal
Clinical ophthalmology
Published
2026-02-01
DOI
https://doi.org/10.2147/opth.s580133
Primary Topic
Artificial Intelligence in Healthcare and Education
Type
article
Field-Weighted Citation Impact
0.00
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Accuracy and Reproducibility of Different Artificial Intelligence Chatbots’ Responses to Patient-Based Vitreoretinal Questions: A Comparative Study

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article

Accuracy and Reproducibility of Different Artificial Intelligence Chatbots’ Responses to Patient-Based Vitreoretinal Questions: A Comparative Study

Mohammed Rashad Baker, Motasem Al-Latayfeh, Dalia Attar, Seren Al Beiruti, Rami Al-Dwairi, Abdelwahab Aleshawi, Mo'men Dayeh, Walaa Awad, Zainah Abu Khalil, Elaf Jarrah, Omar El-Mulki, Lina Alma’aitah, Zaina Qaddoumi
article en

Abstract

ChatGPT-5.o and DeepSeek R1 approached high accuracy and reproducibility comparable to clinical standards, indicating potential as patient-education tools in vitreoretinal care. However, variability across models and disease categories highlights the need for cautious clinical adoption and continued optimization to ensure safe, reliable information delivery.

Clinical ophthalmologyVol. Volume 20
University of Jordan (JO), University of Miami (US), Jordan University of Science and Technology (JO), Hashemite University (JO), The Farah Hospital (JO)
Gender equality
Openalex Percentile: Top 57%
Artificial Intelligence in Healthcare and Education
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