DIA Proteomics Reveals the Mechanism of cAMP Signaling Pathway-Mediated HPT Axis in Regulating Spermatogenesis of Hu Sheep
This study is the first multi-tissue proteomic investigation <b><i>proposing a model in which</i></b> the high reproductive performance of Hu sheep <b><i>is potentially</i></b> linked to the efficient, coordinated regulation of spermatogenesis-related proteins and signaling pathways-particularly in the testis. These findings offer novel insights into the molecular mechanisms of male reproduction in sheep and identify potential targets for future research and breeding applications.
Authors
- S. R. Shi
- Qiaodan Li
- Zhuo Chen (ORCID: https://orcid.org/0000-0002-5351-3489)
- Hao Wang (ORCID: https://orcid.org/0000-0001-6881-9977)
- Xuejiao An
- Zhu Lina
- Binpeng Xi (ORCID: https://orcid.org/0009-0003-6178-9359)
- Rui Zhang
- Yaojing Yue
Institutions
- Minzu University of China (CN)
- Lanzhou Institute of Husbandry and Pharmaceutical Sciences (CN)
- Chinese Academy of Agricultural Sciences (CN)
- Ministry of Agriculture and Rural Affairs (CN)
- Yulin University (CN)
Publication Details
- Journal
- Animals
- Published
- 2026-02-13
- DOI
- https://doi.org/10.3390/ani16040595
- Primary Topic
- Sperm and Testicular Function
- Type
- article
- Field-Weighted Citation Impact
- 0.00