Multi-Modal Metabolomics Deciphers Pan-Cancer Metabolic Landscapes and Spatial-Niche-Specific Alternations
This pan-cancer, multi-scale integrative analysis highlights substantial metabolic heterogeneity within the TME and across cancer types and identifies metabolites with consistent alterations across analytical layers, providing candidate features for future studies of tumor metabolism and potential metabolic biomarkers.
Authors
- Tingze Feng
- Hai-Long Piao
- Di Chen
Institutions
- Dalian Institute of Chemical Physics (CN)
- Dalian University of Technology (CN)
- Liaoning Cancer Hospital & Institute (CN)
- University of Chinese Academy of Sciences (CN)
Publication Details
- Journal
- Metabolites
- Published
- 2026-02-13
- DOI
- https://doi.org/10.3390/metabo16020129
- Primary Topic
- Cancer, Hypoxia, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Liaoning Revitalization Talents Program
- Dalian Institute of Chemical Physics