Functional magnetic resonance imaging insights into nociceptive signal processing network in rat lumbar spinal cord

Our results demonstrate that lumbar enlargement (L3 and L4) was involved in processing heat nociceptive information and bilateral dorsal and ventral horns were strongly interconnected at rest. We hypothesize that the intermediate zone in the rostral subsegment of L3 serves as a modulation center for nociceptive processing within the lumbar cord.

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Publication Details

Journal
PAIN Reports
Published
2026-02-11
DOI
https://doi.org/10.1097/pr9.0000000000001368
Primary Topic
Pain Mechanisms and Treatments
Type
article
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article

Functional magnetic resonance imaging insights into nociceptive signal processing network in rat lumbar spinal cord

Xinqiang Yan, L. Chen, Chaoqi Mu, John C. Gore et al.
PAIN Reports
Pain Mechanisms and Treatments
article

Functional magnetic resonance imaging insights into nociceptive signal processing network in rat lumbar spinal cord

Xinqiang Yan, L. Chen, Chaoqi Mu, John C. Gore, Feng Wang, Xuerong Zhang, Pai-Feng Yang, Ming Lu, Arabinda Mishra
article en

Abstract

Our results demonstrate that lumbar enlargement (L3 and L4) was involved in processing heat nociceptive information and bilateral dorsal and ventral horns were strongly interconnected at rest. We hypothesize that the intermediate zone in the rostral subsegment of L3 serves as a modulation center for nociceptive processing within the lumbar cord.

PAIN ReportsVol. 11(2)
Vanderbilt University (US), Vanderbilt University Medical Center (US)
Openalex Percentile: Top 54%
Pain Mechanisms and Treatments
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