Leucine-rich repeats and immunoglobulin-like domains 3 suppresses hypoxia-induced vasculogenic mimicry in glioma by promoting the ubiquitination and degradation of Snail2

LRIG3 inhibits hypoxia-induced VM in glioma by facilitating the proteasomal degradation of Snail2 via ubiquitination.

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Publication Details

Journal
Cell Stress and Chaperones
Published
2026-02-13
DOI
https://doi.org/10.1016/j.cstres.2026.100152
Primary Topic
Cancer, Hypoxia, and Metabolism
Type
article
Field-Weighted Citation Impact
0.00
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article

Leucine-rich repeats and immunoglobulin-like domains 3 suppresses hypoxia-induced vasculogenic mimicry in glioma by promoting the ubiquitination and degradation of Snail2

Chenghao Peng, Ran Xu, Wenjin Qiu, Yang Guo et al.
Cell Stress and Chaperones
Cancer, Hypoxia, and Metabolism
article

Leucine-rich repeats and immunoglobulin-like domains 3 suppresses hypoxia-induced vasculogenic mimicry in glioma by promoting the ubiquitination and degradation of Snail2

Chenghao Peng, Ran Xu, Wenjin Qiu, Yang Guo, Dongsheng Guo
article en

Abstract

LRIG3 inhibits hypoxia-induced VM in glioma by facilitating the proteasomal degradation of Snail2 via ubiquitination.

Cell Stress and ChaperonesVol. 31(2)
Jiangnan University (CN), Guiyang Medical University (CN), Nantong University (CN), Affiliated Hospital of Nantong University (CN), Affiliated Hospital of Guizhou Medical University (CN), Wuxi Fourth People's Hospital (CN), Tongji Hospital (CN), Huazhong University of Science and Technology (CN)
Openalex Percentile: Top 58%
Cancer, Hypoxia, and Metabolism
DOIOpen Access PDFOpenAlex
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Leucine-rich repeats and immunoglobulin-like domains 3 suppresses hypoxia-induced vasculogenic mimicry in glioma by promoting the ubiquitination and degradation of Snail2 — Chenghao Peng, Ran Xu, et al. · Cell Stress and Chaperones (2026) | TGRS Research Map | TGRS