BCTI: a Bayesian network-based method for revealing critical transitions in complex biological systems
The proposed method enables effective detection of critical transitions and reveals dynamic regulatory mechanisms in complex biological systems, demonstrating strong potential for applications in systems biology, precision medicine, and the exploration of key molecular regulation driving disease progression and development.
Authors
- Hao Peng (ORCID: https://orcid.org/0000-0003-4923-1240)
- Hui Tang (ORCID: https://orcid.org/0000-0001-8856-9127)
- Renhao Hong (ORCID: https://orcid.org/0000-0003-0565-927X)
- Nan Yang (ORCID: https://orcid.org/0000-0002-1954-1064)
- Yuyan Tong
- Rui Liu
- Pei Chen
Institutions
- Foshan University (CN)
- South China University of Technology (CN)
Publication Details
- Journal
- PeerJ
- Published
- 2026-02-13
- DOI
- https://doi.org/10.7717/peerj.20860
- Primary Topic
- Gene Regulatory Network Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00