Development of an Acute Intracranial Hypertension-Induced Rat Model for Terson Syndrome and Mechanisms of Blood-Retinal Barrier Breakdown

This study established a preliminary experimental rat model of Terson syndrome. The model suggests Terson syndrome results from intracranial hypertension compressing the central retinal vein, disrupting tight junctions, and causing blood-retinal barrier failure, leading to hemorrhage.

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Publication Details

Journal
Current Eye Research
Published
2026-02-13
DOI
https://doi.org/10.1080/02713683.2026.2622718
Primary Topic
Child Abuse and Related Trauma
Type
article
Field-Weighted Citation Impact
0.00
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article

Development of an Acute Intracranial Hypertension-Induced Rat Model for Terson Syndrome and Mechanisms of Blood-Retinal Barrier Breakdown

Hai-nan XIE, Qingrong Zhang, Jian-Qiao Ye, Rui Wang et al.
Current Eye Research
Child Abuse and Related Trauma
article

Development of an Acute Intracranial Hypertension-Induced Rat Model for Terson Syndrome and Mechanisms of Blood-Retinal Barrier Breakdown

Hai-nan XIE, Qingrong Zhang, Jian-Qiao Ye, Rui Wang, Yu-Qi Jiang, Hou-Bin Huang
article en

Abstract

This study established a preliminary experimental rat model of Terson syndrome. The model suggests Terson syndrome results from intracranial hypertension compressing the central retinal vein, disrupting tight junctions, and causing blood-retinal barrier failure, leading to hemorrhage.

Current Eye Research
Chinese PLA General Hospital (CN), Huazhong University of Science and Technology Hospital (CN)
Good health and well-being
Openalex Percentile: Top 55%
Child Abuse and Related Trauma
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