Overstaging of the mesorectal fascia following neoadjuvant therapy and its impact on therapeutic management: a single-center retrospective cohort study of 506 mesorectal fascia positive patients

MRI assessment of MRF involvement showed limited concordance with pathological CRM status after NAT. Integration of MRF status and RAS status refines prognostic stratification in non-metastatic MRF-positive rectal cancer, guiding subsequent treatment decisions.

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Publication Details

Journal
Journal of Gastrointestinal Oncology
Published
2026-02-01
DOI
https://doi.org/10.21037/jgo-2025-792
Primary Topic
Colorectal Cancer Surgical Treatments
Type
article
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article

Overstaging of the mesorectal fascia following neoadjuvant therapy and its impact on therapeutic management: a single-center retrospective cohort study of 506 mesorectal fascia positive patients

Yiwei Zeng, Donghui Huang, Ye Xu, Tong Tong et al.
Journal of Gastrointestinal Oncology
Colorectal Cancer Surgical Treatments
article

Overstaging of the mesorectal fascia following neoadjuvant therapy and its impact on therapeutic management: a single-center retrospective cohort study of 506 mesorectal fascia positive patients

Yiwei Zeng, Donghui Huang, Ye Xu, Tong Tong, Huan Zhang, Tianan Guo
article en

Abstract

MRI assessment of MRF involvement showed limited concordance with pathological CRM status after NAT. Integration of MRF status and RAS status refines prognostic stratification in non-metastatic MRF-positive rectal cancer, guiding subsequent treatment decisions.

Journal of Gastrointestinal OncologyVol. 17(1)
Fudan University Shanghai Cancer Center (CN)
No poverty
Openalex Percentile: Top 56%
Colorectal Cancer Surgical Treatments
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