Nomogram-based prediction models for clinical outcomes in pediatric RUNX1::RUNX1T1-positive acute myeloid leukemia: a retrospective analysis from AML-CAMS serial trials
This study established internally validated 3-year OS and RFS nomograms for pediatric <i>RUNX1::RUNX1T1</i>-positive AML with excellent discrimination and clinical utility. Prospective multicenter validation is warranted to confirm the robustness and facilitate clinical adoption.
Authors
- Yingchi Zhang (ORCID: https://orcid.org/0000-0003-2237-7477)
- Meihui Yi (ORCID: https://orcid.org/0000-0003-4065-2380)
- Yupeng Zheng (ORCID: https://orcid.org/0000-0002-2165-7859)
- Tianyuan Hu
- Yumei Chen
- W Y Yang
- X F Zhu
- Y Guo
- L Zhang
- Y Zou
- Min Ruan
- Xiaojuan Chen
- Xiaoli Chen
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
- National Clinical Research (US)
- Institute of Hematology & Blood Diseases Hospital (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2026-02-13
- DOI
- https://doi.org/10.3389/fonc.2026.1744352
- Primary Topic
- Acute Myeloid Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Ministry of Science and Technology of the People's Republic of China
- Chinese Academy of Medical Sciences