Kaempferol Attenuates Oxidative Stress‐Induced Injury in Gastric Mucosal Cells by Activating Nrf2/GPX4 Axis to Inhibit Ferroptosis
KAE protects against H₂O₂-induced gastric epithelial damage through activating the Nrf2/GPX4 axis, thereby lowering oxidative injury and ferroptotic processes, and offering a potential therapeutic strategy for gastric mucosal protection.
Authors
- Chao Luo
- Xiong Xiao
- Jing Yan
- Zhiguang Sun
- Yun Shen
Institutions
- Nanjing University of Chinese Medicine (CN)
- Second Affiliated Hospital of Nanjing Medical University (CN)
- Nanjing Second Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Immunity Inflammation and Disease
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1002/iid3.70352
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Government of Jiangsu Province
- Nanjing University