A novel murine model of Sjögren’s disease using lacrimal autoantigen

The LGSS mice have been shown that successfully replicates several key features of SjD and demonstrates significant lacrimal gland and ocular surface damages, making it a valuable animal model to study SjD-DE.

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Publication Details

Journal
Frontiers in Immunology
Published
2026-02-13
DOI
https://doi.org/10.3389/fimmu.2026.1586519
Primary Topic
Salivary Gland Disorders and Functions
Type
article
Field-Weighted Citation Impact
0.00
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article

A novel murine model of Sjögren’s disease using lacrimal autoantigen

S X Liu, Yaqiong Li, F.Y. Lei, Y Jie et al.
Frontiers in Immunology
Salivary Gland Disorders and Functions
article

A novel murine model of Sjögren’s disease using lacrimal autoantigen

S X Liu, Yaqiong Li, F.Y. Lei, Y Jie, Siyuan Li, Lei Tian, Peng Zhang
article en

Abstract

The LGSS mice have been shown that successfully replicates several key features of SjD and demonstrates significant lacrimal gland and ocular surface damages, making it a valuable animal model to study SjD-DE.

Frontiers in ImmunologyVol. 17
Beijing Tongren Hospital (CN), Capital Medical University (CN), Beijing Advanced Sciences and Innovation Center (CN), Beihang University (CN)
Good health and well-being
Openalex Percentile: Top 54%
Salivary Gland Disorders and Functions
DOIOpen Access PDFOpenAlex
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