Mapping the intersection of social status and comorbidity in knee osteoarthritis: A WOMAC-based study

Knee osteoarthritis (OA) is a disabling joint condition that leads to extreme morbidityand quality of life impairment, particularly among older adults. This study aimed to investigate the socio-demographic factors and comorbid conditions influencing the severity of symptoms of knee OA using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Data were derived from 622 patients across 9 months from the major healthcare facilities of Dhaka. This study found age, sex, educational status, obesity, diabetes mellitus, and cardiovascular disease (CVD) were predictors for the severity of symptoms of OA of the knee. Female participants were more prone to have severe symptoms compared to males, and those who were more than 70-years-old were at greater risk of severe symptoms. Low educational status, obesity, diabetes mellitus, and CVD were also predictors for severe OA of the knee. Age (p < 0.001), obesity (p < 0.001), and diabetes (p < 0.001) were the best predictors of severity of symptoms based on the multinomial logistic regression analysis. The findings from the study highlighted the associated factors of knee OA and the need for integral healthcare measures that address both the socio-economic and the physical determinants. Focused interventions need to be employed, particularly for high-risk groups such as the elderly, women, and the comorbid, to minimize the incidence of OA of the knee and maximize the outcomes for patients in settings such as that of Bangladesh, where resources may not be available.

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Publication Details

Journal
PLoS ONE
Published
2026-02-13
DOI
https://doi.org/10.1371/journal.pone.0324767
Primary Topic
Osteoarthritis Treatment and Mechanisms
Type
article
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0.00
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article

Mapping the intersection of social status and comorbidity in knee osteoarthritis: A WOMAC-based study

Mohoshina Karim, Marzana Afrooj Ria, Tasrima Trisha Ratna, Fatema Priyanka et al.
PLoS ONE
Osteoarthritis Treatment and Mechanisms
article

Mapping the intersection of social status and comorbidity in knee osteoarthritis: A WOMAC-based study

Mohoshina Karim, Marzana Afrooj Ria, Tasrima Trisha Ratna, Fatema Priyanka, Ilat-E-Mees Subah, Umme Salma, Rahnuma Hossain Twasin, Joynal Abedin Imran, Md Delwar Hossen, Shahriar Hasan
article en

Abstract

Knee osteoarthritis (OA) is a disabling joint condition that leads to extreme morbidityand quality of life impairment, particularly among older adults. This study aimed to investigate the socio-demographic factors and comorbid conditions influencing the severity of symptoms of knee OA using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Data were derived from 622 patients across 9 months from the major healthcare facilities of Dhaka. This study found age, sex, educational status, obesity, diabetes mellitus, and cardiovascular disease (CVD) were predictors for the severity of symptoms of OA of the knee. Female participants were more prone to have severe symptoms compared to males, and those who were more than 70-years-old were at greater risk of severe symptoms. Low educational status, obesity, diabetes mellitus, and CVD were also predictors for severe OA of the knee. Age (p < 0.001), obesity (p < 0.001), and diabetes (p < 0.001) were the best predictors of severity of symptoms based on the multinomial logistic regression analysis. The findings from the study highlighted the associated factors of knee OA and the need for integral healthcare measures that address both the socio-economic and the physical determinants. Focused interventions need to be employed, particularly for high-risk groups such as the elderly, women, and the comorbid, to minimize the incidence of OA of the knee and maximize the outcomes for patients in settings such as that of Bangladesh, where resources may not be available.

PLoS ONEVol. 21(2)
North South University (BD), University of Dhaka (BD), ASA University Bangladesh (BD), National Institute of Traumatology & Orthopaedic Rehabilitation (BD), Dhaka Medical College and Hospital (BD)
Openalex Percentile: Top 57%
Osteoarthritis Treatment and Mechanisms
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