Improving reliability and accuracy of structured data extraction using a consensus large-language model approach–a use case description in multiple sclerosis

Our method enables fast and reliable LLM-based analysis of large clinical routine data sets of varying complexity with a low technical barrier to entry. By generating an LLM consensus, we were able to considerably improve the quality of the output making it comparable to data created by neurology specialists. This approach allows large amounts of unstructured data to be analyzed in a time and cost-efficient manner. Nevertheless, the evaluation of errors in results produced by LLM remains difficult. Scientific work using such methods must continue to be subject to strict testing of the validity of the method in the future.

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Publication Details

Journal
Frontiers in Artificial Intelligence
Published
2026-02-13
DOI
https://doi.org/10.3389/frai.2026.1658575
Citations
1
Primary Topic
Multiple Sclerosis Research Studies
Type
article
Field-Weighted Citation Impact
36.00
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article

Improving reliability and accuracy of structured data extraction using a consensus large-language model approach–a use case description in multiple sclerosis

E. Reuter, Anke Salmen, Rafael Klimas, Philip Lennart Poser et al.
1 citations
Frontiers in Artificial Intelligence
Multiple Sclerosis Research Studies
36.00
article

Improving reliability and accuracy of structured data extraction using a consensus large-language model approach–a use case description in multiple sclerosis

E. Reuter, Anke Salmen, Rafael Klimas, Philip Lennart Poser, Christoph Hanefeld, Ralf Gold, Jeremias Motte, Justus Luerweg
article en
1 citations

Abstract

Our method enables fast and reliable LLM-based analysis of large clinical routine data sets of varying complexity with a low technical barrier to entry. By generating an LLM consensus, we were able to considerably improve the quality of the output making it comparable to data created by neurology specialists. This approach allows large amounts of unstructured data to be analyzed in a time and cost-efficient manner. Nevertheless, the evaluation of errors in results produced by LLM remains difficult. Scientific work using such methods must continue to be subject to strict testing of the validity of the method in the future.

Frontiers in Artificial IntelligenceVol. 9
St. Josef-Hospital (DE), Katholisches Klinikum Bochum (DE), Ruhr University Bochum (DE)
Openalex Percentile: Top 1%
Multiple Sclerosis Research Studies
36.00
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