Ventricular entry and postoperative leptomeningeal metastasis after resection of supratentorial high-grade glioma

Tumors with EC predict higher LM risk and shorter OS, while VE during resection does not increase LM risk or worsen OS. Surgeons can use VE to maximize resection of supratentorial HGGs without increasing the risk of subsequent LM.

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Publication Details

Journal
Journal of neurosurgery
Published
2026-02-01
DOI
https://doi.org/10.3171/2025.9.jns25526
Primary Topic
Glioma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
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article

Ventricular entry and postoperative leptomeningeal metastasis after resection of supratentorial high-grade glioma

Maria A. Gubbiotti, Dima Suki, Ben A. Strickland, Christina Abi Faraj et al.
Journal of neurosurgery
Glioma Diagnosis and Treatment
article

Ventricular entry and postoperative leptomeningeal metastasis after resection of supratentorial high-grade glioma

Maria A. Gubbiotti, Dima Suki, Ben A. Strickland, Christina Abi Faraj, G.V. Rao, Heather Yan Lin, Amy B. Heimberger, Thomas Hendrix Beckham, Raymond Sawaya, Barbara J O’Brien, Salmaan Ahmed, Jeffrey S. Weinberg, Frederick F. Lang, Rory R. Mayer, Sujit Prabhu, Sherise D. Ferguson, J. Matthew Debnam, Ian E. McCutcheon
article en

Abstract

Tumors with EC predict higher LM risk and shorter OS, while VE during resection does not increase LM risk or worsen OS. Surgeons can use VE to maximize resection of supratentorial HGGs without increasing the risk of subsequent LM.

Journal of neurosurgery
Northwestern University (US), The University of Texas MD Anderson Cancer Center (US), Medical University of South Carolina (US), Baylor College of Medicine (US), Heliophysics (US), Cancer Research And Biostatistics (US), American University of Beirut Medical Center (LB), Central Texas Spine Institute (US), American University of Beirut (LB)
Good health and well-being
Openalex Percentile: Top 57%
Glioma Diagnosis and Treatment
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