Host proteins associated with strong neutralizing SARS-CoV-2 antibody responses in a South African cohort

These results show that host proteins and pathways involved early in SARS-CoV-2 infection associate with neutralizing antibody levels elicited by the infection at convalescence.

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Publication Details

Journal
Communications Medicine
Published
2026-02-13
DOI
https://doi.org/10.1038/s43856-026-01427-7
Primary Topic
SARS-CoV-2 and COVID-19 Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Host proteins associated with strong neutralizing SARS-CoV-2 antibody responses in a South African cohort

Sashkia R. Balla, Mallory Bernstein, Kajal Reedoy, Zesuliwe Jule et al.
Communications Medicine
SARS-CoV-2 and COVID-19 Research
article

Host proteins associated with strong neutralizing SARS-CoV-2 antibody responses in a South African cohort

Sashkia R. Balla, Mallory Bernstein, Kajal Reedoy, Zesuliwe Jule, Thandeka Moyo-Gwete, Afrah Khairallah, Yashica Ganga, Alice Piller, Farina. Karim, Khadija Khan, Alex Sigal, Bernadett I. Gosnell, Penny L. Moore, Mahomed-Yunus S. Moosa, Thumbi Ndung’u
article en

Abstract

These results show that host proteins and pathways involved early in SARS-CoV-2 infection associate with neutralizing antibody levels elicited by the infection at convalescence.

Communications Medicine
National Health Laboratory Service (ZA), South African Medical Research Council (ZA), University of the Witwatersrand (ZA), Hebrew University of Jerusalem (IL), Ragon Institute of MGH, MIT and Harvard (US), Africa Health Research Institute (ZA), University College London (GB), University of KwaZulu-Natal (ZA)
Openalex Percentile: Top 55%
SARS-CoV-2 and COVID-19 Research
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