A real-world study of adverse event profiles associated with the four key components of antibody–drug conjugates based on the FAERS database
This large-scale real-world evaluation reveals clear component type-specific toxicity signatures among ADCs, supporting more targeted safety monitoring and informing rational ADC design.
Authors
- Shufen Zhang (ORCID: https://orcid.org/0000-0003-3390-4199)
- C. Ye
- Ying Xu (ORCID: https://orcid.org/0000-0002-2401-7718)
- Miao Wang
- Jiaxuan Zhu
Institutions
- Xinjiang Medical University (CN)
- Wenzhou Medical University (CN)
- Fifth Affiliated Hospital of Xinjiang Medical University (CN)
- Hangzhou Medical College (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2026-02-13
- DOI
- https://doi.org/10.3389/fphar.2026.1702195
- Primary Topic
- HER2/EGFR in Cancer Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Zhejiang Pharmaceutical Association
- Bijzonder Onderzoeksfonds UGent
- Natural Science Foundation of Zhejiang Province