TPX2 promotes gastric cancer progression and angiogenesis via Wnt/β-catenin signaling

By activating the Wnt/β-catenin pathway, TPX2 promotes GC migration, invasion, and tumor angiogenesis, which collectively drive GC malignant progression.

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Publication Details

Journal
Frontiers in Oncology
Published
2026-02-13
DOI
https://doi.org/10.3389/fonc.2026.1764583
Primary Topic
Wnt/β-catenin signaling in development and cancer
Type
article
Field-Weighted Citation Impact
0.00
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article

TPX2 promotes gastric cancer progression and angiogenesis via Wnt/β-catenin signaling

Weibo Zhang, Li Xu
Frontiers in Oncology
Wnt/β-catenin signaling in development and cancer
article

TPX2 promotes gastric cancer progression and angiogenesis via Wnt/β-catenin signaling

Weibo Zhang, Li Xu
article en

Abstract

By activating the Wnt/β-catenin pathway, TPX2 promotes GC migration, invasion, and tumor angiogenesis, which collectively drive GC malignant progression.

Frontiers in OncologyVol. 16
Soochow University (CN), Shenyang Anorectal Hospital (CN), Zhangjiagang First People's Hospital (CN)
Good health and well-being
Openalex Percentile: Top 57%
Wnt/β-catenin signaling in development and cancer
DOIOpen Access PDFOpenAlex
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TPX2 promotes gastric cancer progression and angiogenesis via Wnt/β-catenin signaling — Weibo Zhang, Li Xu · Frontiers in Oncology (2026) | TGRS Research Map | TGRS