Safety of carotid endarterectomy in the elderly and octogenarian population: a nationwide study including 80,000 patients
CEA is associated with a worse risk profile among octogenarians. Nonetheless, comorbidity burden and functional status are stronger predictors of adverse outcomes, as compared to age alone. CEA can be performed safely in carefully selected octogenarians with low to moderate comorbidity, whereas severe comorbidity or dependency may represent relative contraindications. Surgical candidacy should be guided by physiological reserve and function rather than chronological age alone.
Authors
- Ziad Khabbaz
- Victor E. Staartjes (ORCID: https://orcid.org/0000-0003-1039-2098)
- Wi Jin Kim (ORCID: https://orcid.org/0000-0002-0073-5408)
- Michael Anthony Rizzuto (ORCID: https://orcid.org/0000-0001-7743-4454)
- Victor Gabriel El-Hajj (ORCID: https://orcid.org/0000-0001-9479-761X)
- Nathaniel R. Ellens (ORCID: https://orcid.org/0000-0001-6901-1160)
- Joanna M. Roy (ORCID: https://orcid.org/0000-0002-4829-1869)
- Rabab Alshahrani
- Adrian Elmi-Terander (ORCID: https://orcid.org/0000-0002-3776-6136)
- Basel Musmar
- Robert H. Rosenwasser
- Stavropoula Tjoumakaris
- Ramachandra P. Tummala
- M. Reid Gooch
- Pascal Jabbour
Institutions
- Thomas Jefferson University Hospital (US)
- Trillium Health Centre (CA)
- Karolinska Institutet (SE)
- University Hospital of Zurich (CH)
- Twin Cities Orthopedics (US)
- Hôtel-Dieu de France (LB)
- Neurological Surgery (US)
- Jefferson Hospital for Neuroscience (US)
Publication Details
- Journal
- Neurosurgical Review
- Published
- 2026-02-14
- DOI
- https://doi.org/10.1007/s10143-026-04174-4
- Primary Topic
- Cerebrovascular and Carotid Artery Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00