Exploratory analysis of high-altitude effects on brain morphology and myelination in native Tibetan infants

ICV was significantly increased in the high-altitude group compared to the sea-level group, especially in altitude areas above 4,000 m. Additionally, delayed myelination in the MCP was observed in the high-altitude group.

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Publication Details

Journal
Translational Pediatrics
Published
2026-02-01
DOI
https://doi.org/10.21037/tp-2025-aw-778
Primary Topic
Neonatal and fetal brain pathology
Type
article
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0.00
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article

Exploratory analysis of high-altitude effects on brain morphology and myelination in native Tibetan infants

Jungang Liu, Wangjiu Cidan, Qing Zhou, Dan Wu et al.
Translational Pediatrics
Neonatal and fetal brain pathology
article

Exploratory analysis of high-altitude effects on brain morphology and myelination in native Tibetan infants

Jungang Liu, Wangjiu Cidan, Qing Zhou, Dan Wu, Rui Hua, Jieyi Chen, Liyuan Hu, Feng Shi, Guoqiang Cheng, Zehong Cao, Rong Zhao, Bi Ze, Yan Zeng, Kai Yan, Wenhao Zhou
article en

Abstract

ICV was significantly increased in the high-altitude group compared to the sea-level group, especially in altitude areas above 4,000 m. Additionally, delayed myelination in the MCP was observed in the high-altitude group.

Translational PediatricsVol. 15(2)
Tibet Autonomous Region People's Hospital (CN), United Imaging Healthcare (China) (CN), Children's Hospital of Fudan University (CN), Children’s Hospital of Fudan University Xiamen Branch (CN), Zhejiang University (CN), Guangzhou Medical University (CN)
Life below water
Openalex Percentile: Top 55%
Neonatal and fetal brain pathology
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