Ultrasound in the diagnosis and management of plantar fibromatosis (ledderhose disease): A case report

Plantar fibromatosis, also known as Ledderhose disease, is a rare benign fibroproliferative disorder of the plantar fascia, characterized by the development of slowly growing nodules that may become painful and functionally limiting. Although the diagnosis is often suspected clinically, imaging-particularly ultrasound-plays an important role in confirming the diagnosis and guiding management. We report the case of a 57-year-old man presenting with bilateral plantar nodules, in whom ultrasound enabled diagnostic confirmation and guided corticosteroid injection. Conservative management combining ultrasound-guided injection, custom orthotic insoles, and a targeted rehabilitation program resulted in complete pain relief and a reduction in nodule size at short-term follow-up. This case illustrates the diagnostic and interventional value of ultrasound in the nonsurgical management of plantar fibromatosis.

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Publication Details

Journal
Radiology Case Reports
Published
2026-02-13
DOI
https://doi.org/10.1016/j.radcr.2026.01.038
Primary Topic
Dupuytren's Contracture and Treatments
Type
article
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article

Ultrasound in the diagnosis and management of plantar fibromatosis (ledderhose disease): A case report

Iman Akhrif, Samia Karkouri, Khaoula Mestour, Sara Skalli
Radiology Case Reports
Dupuytren's Contracture and Treatments
article

Ultrasound in the diagnosis and management of plantar fibromatosis (ledderhose disease): A case report

Iman Akhrif, Samia Karkouri, Khaoula Mestour, Sara Skalli
article en

Abstract

Plantar fibromatosis, also known as Ledderhose disease, is a rare benign fibroproliferative disorder of the plantar fascia, characterized by the development of slowly growing nodules that may become painful and functionally limiting. Although the diagnosis is often suspected clinically, imaging-particularly ultrasound-plays an important role in confirming the diagnosis and guiding management. We report the case of a 57-year-old man presenting with bilateral plantar nodules, in whom ultrasound enabled diagnostic confirmation and guided corticosteroid injection. Conservative management combining ultrasound-guided injection, custom orthotic insoles, and a targeted rehabilitation program resulted in complete pain relief and a reduction in nodule size at short-term follow-up. This case illustrates the diagnostic and interventional value of ultrasound in the nonsurgical management of plantar fibromatosis.

Radiology Case ReportsVol. 21(5)
Mohammed V University (MA)
Good health and well-being
Openalex Percentile: Top 58%
Dupuytren's Contracture and Treatments
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Ultrasound in the diagnosis and management of plantar fibromatosis (ledderhose disease): A case report — Iman Akhrif, Samia Karkouri, et al. · Radiology Case Reports (2026) | TGRS Research Map | TGRS