Extracellular vesicles from human adipose-derived stem cells relieve pain and inflammation in a rat model of knee osteoarthritis
hASC-EVs exhibited robust pain-relieving and cartilage-preserving effects in an OA rat model, highlighting their potential as a promising cell-free therapeutic strategy for the management of OA-related pain and joint degeneration.
Authors
- Chang Hee Woo (ORCID: https://orcid.org/0000-0003-2365-3269)
- Ye Eun Yun (ORCID: https://orcid.org/0000-0001-9676-1020)
- Young Chan Choi
- Ji Suk Choi
- Woo Sung Kim
- Kyoung Soo Lee
- Yong Woo Cho
Institutions
- Comtech Telecommunications (United States) (US)
- Hanyang University (KR)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2026-02-13
- DOI
- https://doi.org/10.1186/s13287-026-04932-7
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00