Addressing unmet needs in relapsed/refractory multiple myeloma: an Italian Delphi consensus on current challenges and emerging therapies

Despite multiple available agents and combinations, effective treatment of all patients with relapsed/refractory multiple myeloma remains a major unmet need. Given their distinct mechanism of action, immunotherapies hold significant potential to address this gap and improve clinical outcomes.

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Publication Details

Journal
Frontiers in Oncology
Published
2026-02-13
DOI
https://doi.org/10.3389/fonc.2026.1756247
Primary Topic
Multiple Myeloma Research and Treatments
Type
article
Field-Weighted Citation Impact
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article

Addressing unmet needs in relapsed/refractory multiple myeloma: an Italian Delphi consensus on current challenges and emerging therapies

Paola La Malfa, Elena Zamagni, Renato Zambello, M. Cavo et al.
Frontiers in Oncology
Multiple Myeloma Research and Treatments
article

Addressing unmet needs in relapsed/refractory multiple myeloma: an Italian Delphi consensus on current challenges and emerging therapies

Paola La Malfa, Elena Zamagni, Renato Zambello, M. Cavo, Rachele Freddi, Massimo Offidani, Francesco Berruto, M. Petrucci, Gabriele Buda, Sara Bringhen, Francesco Di Raimondo, Pellegrino Musto
article en

Abstract

Despite multiple available agents and combinations, effective treatment of all patients with relapsed/refractory multiple myeloma remains a major unmet need. Given their distinct mechanism of action, immunotherapies hold significant potential to address this gap and improve clinical outcomes.

Frontiers in OncologyVol. 16
University of Padua (IT), Policlinico Umberto I (IT), IQVIA (United Kingdom) (GB), Azienda Universitaria Ospedaliera Consorziale - Policlinico Bari (IT), Azienda Ospedaliero-Universitaria di Modena (IT), Azienda Ospedaliero-Universitaria Careggi (IT), Precision for Medicine (United States) (US), Policlinico Universitario di Catania (IT), Azienda Sanitaria Ospedaliera S.Croce e Carle Cuneo (IT), Istituti di Ricovero e Cura a Carattere Scientifico (IT), IQ Solutions (US), Azienda Ospedaliero Universitaria Policlinico "G.Rodolico - San Marco" (IT), Azienda Ospedaliera Universitaria Pisana (IT), University of Bologna (IT)
Good health and well-being
Openalex Percentile: Top 55%
Multiple Myeloma Research and Treatments
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Addressing unmet needs in relapsed/refractory multiple myeloma: an Italian Delphi consensus on current challenges and emerging therapies — Paola La Malfa, Elena Zamagni, et al. · Frontiers in Oncology (2026) | TGRS Research Map | TGRS