Seizure‐type–specific disruption of hypercapnic cardioventilatory responses in epilepsy models
These data support seizure-type-specific disruption of chemoreflex-autonomic integration. Extending clinical hypercapnic ventilatory response (HCVR) testing, a hypercapnic cardioventilatory response (HCCVR), that is, a combined f<sub>B</sub>, HR, and HRV readout, may help to refine SUDEP risk stratification beyond seizure frequency and type.
Authors
- Auriane Apaire
- Riëm El Tahry
- Acedo Elena Reina
- Elise Jeanne Alice E Collard
- Abigaïl Niyibizi
- Enrique Ignacio Germany Morrison
- Ayse Dereli
Institutions
- Cliniques Universitaires Saint-Luc (BE)
- Université Libre de Bruxelles (BE)
- Walloon Excellence in Lifesciences and Biotechnology (BE)
- UCLouvain (BE)
Publication Details
- Journal
- Epilepsia
- Published
- 2026-02-17
- DOI
- https://doi.org/10.1002/epi.70123
- Primary Topic
- Neuroscience of respiration and sleep
- Type
- article
- Field-Weighted Citation Impact
- 0.00