Effects of IKAP Health Education and Exercise Therapy on Clinical Outcomes in Hypertensive Intracerebral Hemorrhage

The study aims to investigate the effects of the Information-Knowledge-Attitude-Practice (IKAP) health education combined with exercise therapy model on electrolyte homeostasis, liver function, and kidney function in patients with hypertensive intracerebral hemorrhage (HICH), and to construct a multidimensional biomarker-based multiple organ dysfunction syndrome (MODS) risk prediction model to provide new strategies for organ function support therapy in critically ill patients. A total of 102 HICH patients admitted between October 2023 and June 2025 (inclusive) were enrolled and underwent IKAP health education and staged exercise rehabilitation training. Blood tests (WBC, RBC, HGB, CRP), electrolyte levels (Na⁺, K⁺, Cl-, Ca2⁺), liver function (ALB, ALT, AST, ALP, TBIL, GGT), and kidney function (BUN, Scr, UA) were measured before and after care, and the incidence of MODS was calculated. Logistic regression analysis was used to identify independent risk factors for MODS, establish a risk prediction model, and validate its efficacy. The post-care levels of WBC, CRP, Na⁺, K⁺, BUN, Scr, UA, ALT, AST, and GGT were significantly lower than pre-care levels (p<0.05). Multivariate logistic regression analysis identified CRP, K⁺, Scr, UA, and GGT as independent risk factors for MODS. The ROC curve AUC for predicting MODS was 0.9195, with a sensitivity of 74.07% and specificity of 94.67%. Conclusively, IKAP health education combined with exercise therapy improves electrolyte homeostasis and liver function and kidney function in HICH patients. The MODS risk prediction model based on CRP, K⁺, Scr, UA, and GGT demonstrates high sensitivity and specificity.