Risks of dementia and stroke in patients with hypertension using telmisartan or other renin‑angiotensin system inhibitors

Whether telmisartan is associated with a reduced risk of dementia compared to other RAS inhibitors in patients with HTN and varying blood sugar levels remains unclear. Our cohort study aimed to investigate the long-term cognitive and cerebrovascular outcomes of hypertensive patients receiving telmisartan compared to those receiving other RAS inhibitors. Eligible individuals were categorized into three groups. Use of telmisartan may be associated with marginally lower risks of all dementia and stroke compared with other RAS inhibitors in patients with HTN.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2026-02-01
DOI
https://doi.org/10.1002/alz.71153
Primary Topic
Renin-Angiotensin System Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Risks of dementia and stroke in patients with hypertension using telmisartan or other renin‑angiotensin system inhibitors

Chi‐Hung Liu, Yi‐Chia Wei, Ning‐I Yang, Ming‐Lung Tsai et al.
Alzheimer s & Dementia
Renin-Angiotensin System Studies
article

Risks of dementia and stroke in patients with hypertension using telmisartan or other renin‑angiotensin system inhibitors

Chi‐Hung Liu, Yi‐Chia Wei, Ning‐I Yang, Ming‐Lung Tsai, Tien‐Hsing Chen, Ting‐Yu Chang
article en

Abstract

Whether telmisartan is associated with a reduced risk of dementia compared to other RAS inhibitors in patients with HTN and varying blood sugar levels remains unclear. Our cohort study aimed to investigate the long-term cognitive and cerebrovascular outcomes of hypertensive patients receiving telmisartan compared to those receiving other RAS inhibitors. Eligible individuals were categorized into three groups. Use of telmisartan may be associated with marginally lower risks of all dementia and stroke compared with other RAS inhibitors in patients with HTN.

Alzheimer s & DementiaVol. 22(2)
Chang Gung University of Science and Technology (TW), Chang Gung University (TW), National Taipei University of Nursing and Health Science (TW), Chang Gung Memorial Hospital (TW), Taipei Municipal YangMing Hospital (TW), Keelung Chang Gung Memorial Hospital (TW), Linkou Chang Gung Memorial Hospital (TW)
Chang Gung Medical Foundation, National Science and Technology Council
Openalex Percentile: Top 59%
Renin-Angiotensin System Studies
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Risks of dementia and stroke in patients with hypertension using telmisartan or other renin‑angiotensin system inhibitors — Chi‐Hung Liu, Yi‐Chia Wei, et al. · Alzheimer s & Dementia (2026) | TGRS Research Map | TGRS